basic FUNCTION
| involved in the cholesterol biosynthetic pathway (first step) |
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enzyme that determines the switch toward sterol biosynthesis  |
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in prostate cancer cells its expression is enhanced by androgens, channeling intermediates of the mevalonate/isoprenoid pathway toward cholesterol synthesis  |
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plays an important role in the cholesterol biosynthesis pathway as it is responsible for the flow of metabolites into either the sterol or the non-sterol branches of the pathway  |
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may be involved in the etiology of hypercholesterolemia  |
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key enzyme for endogenous cholesterol production, in the neural stem and progenitor cells of the ventricular zone (VZ)  |
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plays a role in barrier permeability and integrity  |
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may play an important role in prostate cancer development and its aggressive phenotypes  |
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divalent metal-ion-dependent enzyme that catalyzes the two-step reductive `head-to-head' condensatio  |