| basic FUNCTION
| catalyzing the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X |
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promoting the prenylation of Ras |
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first step of a series of post translational modification of RAS |
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attachment of an isoprenoid lipid (a process termed prenylation) by FNTA or geranylgeranyltransferase type I (PGGT1B) is essential for the function of many signal transduction proteins involved in growth, differentiation, and oncogenesis  |
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required for its association with the inner surface of the plasma membrane |
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also involved in maturation of other proteins including Ras familymembers, the gamma subunit of G proteins and nuclear lamins |
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acting as an acetylcholine receptor regulator |
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mediates posttranslational modification of proteins with isoprenoid lipids |
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functions of FNTA subunit that includes control of intracellular membrane trafficking |
