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FLASH GENE

Symbol

LCN1

contributors: npt/ - updated : 05-12-2007

HGNC name	lipocalin 1 (tear prealbumin)
HGNC id	6525

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	5.09 kb     7 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

Map	cen - D9S1112 - D9S1793 - D9S66 - D9S1818 - D9S23 - D9S31 - LCN1 /D9S1826 - D9S67 - D9S17 - D9S158 - D9S207 - D9S1838 - qter
Authors	Lacazette (97)

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed LCN1 7 - 786 - 176 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive mouth           salivary gland         Respiratory respiratory tract trachea       Visual eye           eye lacrimal gland

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular

cell lineage
cell lines
fluid/secretion	nasal mucus

at STAGE

PROTEIN

PHYSICAL PROPERTIES		Hydrophobic
STRUCTURE

motifs/domains

a single eight-stranded continuously hydrogen-bonded antiparallel beta-barrel which encloses an internal ligand binding site

HOMOLOGY

Homologene

FAMILY	lipophilic ligand carrier protein superfamily
	lipocalin family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION

basic FUNCTION

involved in the transport of hydrophobic ligands

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

constituent of human tear

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS