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FLASH GENE
Symbol MPG contributors: - updated : 20-05-2005
HGNC name N-methylpurine-DNA glycosylase
HGNC id 7211
DNA
TYPE functioning gene
STRUCTURE 6.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Map pter - IL9RP3 - MPG - LCR-HBA@ - HB-A@ - D16S60 - D16S215 - D16S213 - D16S53 - cen
Authors Deng (92), Flint (97)
regionally located 75kb upstream HBZ
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines highly in adenocarcinoma cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleoplasm
basic FUNCTION
  • DNA glycosylase, 3-methyl-adenine,base excision repair
  • functioning as a trranscriptional repressor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding damage DNA
    RNA
    small molecule
    protein
  • RAD23 (damage recognition proteins in excision repair pathways)
  • MBD1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS