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FLASH GENE

Symbol

CRAT

contributors: mct - updated : 14-03-2018

HGNC name	carnitine acetyltransferase
HGNC id	2342

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CRATD

related resource

MITOP database

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function decreased function in the brain of Alzeihmer patients constitutional         gene silencing disrupted mitochondrial bioenergetics resulting in reduced ATP generation and decreased NO signaling constitutional       loss of function has previously been shown to result in muscle insulin resistance due to accumulation of long-chain acylcarnitines

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS