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FLASH GENE

Symbol

IFNB1

contributors: mct - updated : 26-03-2020

HGNC name	interferon, beta 1, fibroblast
HGNC id	5434

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	overexpression of Ifnb1 in the CNS of adult wild-type mice, but not of mice lacking IFN-I receptor on their microglia, induces an ageing-like transcriptional microglial signature, and impairs cognitive performance
	Ifnb mutant mice is a model for sporadic Lewy body and Parkinson's disease dementia