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FLASH GENE
Symbol NPY2R last update : 22-04-2005
HGNC name neuropeptide Y receptor Y2
HGNC id 7957
Location 4q31
DNA RNA EXP/sub-loc PROTEIN PATHOLOGY
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Physical map
LOC391706 4 similar to ribosomal protein S3a; 40S ribosomal protein S3a; v-fos transformation effector protein 1 FLJ32028 4q31.3 hypothetical protein FLJ32028 TIGD4 4q31.23 tigger transposable element derived 4 ARFIP1 4q31.3 ADP-ribosylation factor interacting protein 1 (arfaptin 1) LOC152667 4q31.3 similar to NEFA-interacting nuclear protein NIP30 KIAA1727 4q31.3 KIAA1727 protein LOC389234 4 LOC389234 TRIM2 4q31.3 tripartite motif-containing 2 ANXA2P1 4q21-q31 annexin A2 pseudogene 1 GAJ 4q31.3 GAJ protein KIAA0922 4q31.23 GAJ protein LOC285532 4q31.3 similar to JM5 protein TLR2 4q32 toll-like receptor 2 LOC285533 4q31.3 hypothetical protein LOC285533 SFRP2 4q31.3 secreted frizzled-related protein 2 FLJ20047 4q31.3 hypothetical protein FLJ20047 LOC389235 4 similar to protocadherin 16 precursor; fibroblast cadherin FIB1; fibroblast cadherin 1; dachsous homologue PLRG1 4q31.2-q32.1 pleiotropic regulator 1 (PRL1homolog, Arabidopsis) FGB 4q28 fibrinogen, B beta polypeptide FGA 4q28 fibrinogen, A alpha polypeptide FGG 4q28 fibrinogen, G gamma polypeptide LRAT 4q31.1-q31.23 lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) MGC27016 4q31.3 hypothetical protein MGC27016 LOC389236 4 LOC389236 NPY2R 4q31 neuropeptide Y receptor Y2 LOC389237 4 LOC389237 FLJ21159 4q31.3 hypothetical protein FLJ21159 GUCY1A3 4q31.1-q31.2 guanylate cyclase 1, soluble, alpha 3 GUCY1B3 4q31.3-q33 guanylate cyclase 1, soluble, beta 3 ACCN5 4q31.3-q32 amiloride-sensitive cation channel 5, intestinal TDO2 4q31-q32 tryptophan 2,3-dioxygenase CTSO 4q31-q32 cathepsin O FTHP2 4q31-q32 ferritin, heavy polypeptide pseudogene 2 PDGFC 4q32 platelet derived growth factor C GLRB 4q31.3 glycine receptor, beta LOC391707 4 similar to Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15) GRIA2 4q32-q33 glutamate receptor, ionotropic, AMPA 2
RNA
TRANSCRIPTS type messenger
EXPRESSION / SUBCELLULAR LOCALIZATION
EXPRESSION (based on citations)
constitutive of
   expressed in
organ(s)
SystemOrgan 1organ 2organ 3organ 4level
Nervousbraindiencephalonhypothalamus  
 brainforebraincerebral cortex  
tissue
SystemTissueS_TissueSs_Tissuelevel
Nervouscentral   
Nervousperipherous   
cells
SystemCell
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
SUBCELLULAR LOCALIZATION     plasma membrane
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
interspecies
 
intraspecies
 
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor
basic FUNCTION
  • neuropeptide Y receptor Y2 rhodopsin-like
  • involved in the presynaptic inhibition of neurotransmitter release
    • implicated in a
    process
    cellular process
    physiological behavioral , cardiovascular , circadian , nervous system
    text
  • circadian rhythm
  • blood pressure
    • pathway
    metabolism
    signaling neurotransmission
    a component
    structural
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding neuropeptide Y (NPY), peptide YY (PYY)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS