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FLASH GENE
Symbol DGUOK contributors: - updated : 11-04-2007
HGNC name deoxyguanosine kinase
HGNC id 2858
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal mitochondrial targeting signal
  • a deoxyguanosine kinase domain
    • mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to murine Dguok
    intraspecies homolog to DCK
    Homologene
    FAMILY DCK/DGK family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • phosphorylation of purine deoxyribonucleotides and of analogs used in the treatment of lymphoproliferative disorders
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MDDS1
    related resource MITOP database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS