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FLASH GENE
Symbol PPP1R11 contributors: mct/ - updated : 24-09-2015
HGNC name protein phosphatase 1, regulatory (inhibitor) subunit 11
HGNC id 9285
PROTEIN
PHYSICAL PROPERTIES Hydrophilic
STRUCTURE
motifs/domains
  • eight potential phosphorylation sites
  • a C terminal PEST pattern
  • a VxW motif
    • HOMOLOGY
    interspecies homolog to murine Tctex 5/Ppp1r11
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • protein phosphatase inhibitor
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • t complex associated
  • PPP1R7 is kept in solution by formation of a ternary complex with PP1 and PPP1R11
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • reciprocal relationship between the levels of the PPP1CC and its regulator PPP1R11, suggesing that complex formation between these polypeptides in testis may prevent proteolysis of PPP1R11 and thus, germ cell apoptosis
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS