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FLASH GENE

Symbol

CCRL2

contributors: mct - updated : 21-10-2013

HGNC name	chemokine (C-C motif) receptor-like 2
HGNC id	1612

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   on synovial neutrophils of rheumatoid arthritis patients tumoral     --over   in glioma promotes cell migration and invasion

Susceptibility

to rheumatoid arthritis

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

CCRL2(-/-) mice showed normal recruitment of circulating DC into the lung, but a defective trafficking of antigen-loaded lung dendritic cells to mediastinal lymph nodes