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FLASH GENE
Symbol HIVEP2 contributors: mct - updated : 18-09-2017
HGNC name human immunodeficiency virus type I enhancer binding protein 2
HGNC id 4921
ANIMAL & CELL MODELS
  • Shn2-deficient mice maintain bone mass at the levels comparable to wild-type sham mice even after ovariectomy-induced bone loss and this correlates with the high levels of mineralization activity in bone marrow cells after ovariectomy
  • deletion of Shn2 and Shn3 in mice impairs growth plate maturation during endochondral ossification but simultaneously results in massively elevated trabecular bone formation
  • Hivep2-knockout mice exhibit several working memory deficits, increased anxiety, and hyperactivity