Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

FLT4

contributors: mct - updated : 14-10-2014

HGNC name	fms-related tyrosine kinase 4
HGNC id	3767

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

HLMN1 , PCLD

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional somatic mutation       in juvenile hemangioma tumoral     --over   in prostate cancer cells (increases the risk of biochemical recurrence in prostate cancer patients treated by radical prostatectomy)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer angiogenesis   blocking EFNB2 signaling in tumours might represent an intriguing strategy to interfere simultaneously with both KDR and FLT4 function that could be used as an alternative or combinatorial anti-angiogenic treatment for tumour therapy

ANIMAL & CELL MODELS