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FLASH GENE
Symbol RDBP contributors: mct/npt - updated : 14-06-2008
HGNC name RD RNA binding protein
HGNC id 13974
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a canonical betaalphabetabetaalphabeta RNA recognition motif (RRM) that binds to a wide variety of RNA sequences
    • conjugated RiboP
    HOMOLOGY
    interspecies homolog to murine D17H6S45
    Homologene
    FAMILY
  • RRM NELF-E family
    • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • new factor that coordinates different mRNA processing steps during transcription
  • negatively regulate transcription elongation by RNA polymerase II (RNAPII)
    • CELLULAR PROCESS nucleotide, transcription, elongation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacts with the nuclear cap binding complex (NCBP1), a multifunctional factor that plays important roles in several mRNA processing steps, and the two factors together participate in the 3' end processing of replication-dependent histone mRNAs
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS