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FLASH GENE
Symbol RDBP contributors: mct/npt - updated : 14-06-2008
HGNC name RD RNA binding protein
HGNC id 13974
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
 salivary gland   highly
Reproductivefemale systemovary  highly
 male systemprostate  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a canonical betaalphabetabetaalphabeta RNA recognition motif (RRM) that binds to a wide variety of RNA sequences
    • conjugated RiboP
    HOMOLOGY
    interspecies homolog to murine D17H6S45
    Homologene
    FAMILY
  • RRM NELF-E family
    • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • new factor that coordinates different mRNA processing steps during transcription
  • negatively regulate transcription elongation by RNA polymerase II (RNAPII)
    • CELLULAR PROCESS nucleotide, transcription, elongation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacts with the nuclear cap binding complex (NCBP1), a multifunctional factor that plays important roles in several mRNA processing steps, and the two factors together participate in the 3' end processing of replication-dependent histone mRNAs
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS