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FLASH GENE

Symbol

MARCKS

contributors: mct/npt/pgu - updated : 20-12-2016

HGNC name	myristoylated alanine-rich protein kinase C substrate
HGNC id	6759

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   associated with poor patient survival in epithelial ovarian cancer (EOC)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive ovary the potential of MARCKS inhibition as a novel stroma-oriented therapy in epithelial ovarian cancer (EOC)

ANIMAL & CELL MODELS

MARCKS-null mouse is embryonic lethal because of severe neural defects