Symbol
| TCF7
| contributors: mct - updated : 19-09-2016
|
HGNC name
| transcription factor 7 (T-cell specific, HMG-box)
|
HGNC id
| 11639
|
Susceptibility
|
asthma to type 1 diabetes (T1D) |
Variant & Polymorphism
SNP
| variant (A) allele of C883A was significantly associated with T1D ![](pubmed.jpg) |
|
|
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | hemopathy | | ![](pubmed.jpg) |
TCF7 and LEF1 transcription factors are novel therapeutic targets in treating hematological malignancies |
| | | |
| TCF7/mice developing adenomas in the gut and mammary glands | |
Tcf1-deficient mice do not have PLZF-expressing thymocytes and eomesodermin-expressing memory-like CD8 thymocytes ![](pubmed.jpg) |