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FLASH GENE

Symbol

DPEP1

contributors: mct - updated : 28-03-2019

HGNC name	dipeptidase 1 (renal)
HGNC id	3002

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in colorectal cancers (CRCs) and high DPEP1 expression levels are associated with poorer patient survival

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	excellent marker of high-grade intraepithelial neoplasia (IEN) and Colorectal cancer (CRC)
Therapy target
	System Type Disorder Pubmed cancer digestive colon it might be a potential therapeutic target for preventing the progression of colon cancer cancer endocrine pancreas DPEP1 may be a candidate target in PDAC for designing improved treatments

ANIMAL & CELL MODELS

Mbd1 deficient mice