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FLASH GENE
Symbol IL9 contributors: mct - updated : 24-05-2016
HGNC name interleukin 9
HGNC id 6029
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immuneactivated B lymphocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine T cell growth factor P40
homolog to C.elegans f28c6.10
Homologene
FAMILY
  • interleukin (IL-7/IL-9) family
    • CATEGORY immunity/defense , signaling cytokine
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • determining factor in controlling bronchial hyperresponsiveness
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS inflammation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • IL4, IL9, IL13 may increase CLCA1 expression in cystic fibrosis but may not have a significant effect on mucus expression
  • SMAD2 and SMAD3 were redundantly essential for TGFB1 signaling to induce histone modifications for IL9 transcription
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to asthma
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS