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Symbol NPR3 contributors: mct/npt - updated : 16-01-2024
HGNC name natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
HGNC id 7945
ANIMAL & CELL MODELS
  • its complete absence, unexpectidly produces skeletal abnormalities in mice
  • continuous infusion of the peptide Ostn, an endogenous ligand of Npr3 secreted by bone and muscle cells, lowered blood pressure in wild-type mice, suggesting that endogenous natriuretic peptides play major roles in the regulation of blood pressure