protein
| interacting with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF) |
|
binding to CCNB1IP1 |
|
CDK5 activation in cells that overexpress CCNG1 leads to MYC phosphorylation on Ser-62, which is responsible for CCNG1-mediated transcriptional activation of CCNB1 |
|
interacting with catalytically active RALBP1 and CDC2 during mitosis to form an endocytotic complex during interphase |
|
overexpression of AURKA may stabilize CCNB1 through inhibiting its degradation |
|
different levels of CCNB1-CDK1 kinase activity trigger different mitotic events, thus revealing how the remarkable reorganization of the cell is coordinated at mitotic entry |
|
CCNA2 helps initiate mitosis, in part through its effects on CCNB1, and CCNB1 and CCNB2 are particularly critical for the maintenance of the mitotic state |
|
CPEB1 is bound and represses cyclin B1 mRNA translation until a signal to proliferate phosphorylates CPEB1, resulting in an increase in cyclin B1 protein and progression into mitosis |
|
TSC2 binds and regulates the G 2/M cyclin, cyclin B1 |
|
CDK1/CCNB1-dependent hyper-phosphorylation of BCL2L11 during prolonged mitotic arrest is an important cell death signal |
|
SPARC induced G2/M cell cycle arrest was mediated through inhibition of the CCNB1-regulated signaling pathway involving CDKN1A and CDC2 expression |
|
STOX1 promotes mitotic entry by binding to the CCNB1 promotor |
|
CARM1 represses replicative senescence by methylating ELAVL1 and thereby enhancing ELAVL1 ability to regulate the turnover of CCNA1, CCNB1, FOS, SIRT1, and CDKN2A mRNAs ( |