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FLASH GENE

Symbol

LTA

contributors: np/ - updated : 23-05-2007

HGNC name	lymphotoxin alpha (TNF superfamily, member 1)
HGNC id	6709

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to myocardial infarction to early-onset leprosy to psoriatic arthritis

Variant & Polymorphism SNP , other	increased risk of myocardial infarction
	(LTA)+80 A allele was significantly associated with an increase in early-onset leprosy risk

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular atheroma cardiac metabolism lipid   may represent a novel therapeutic route for the treatment of dyslipidemia

ANIMAL & CELL MODELS