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FLASH GENE

Symbol

SPARC

contributors: mct - updated : 02-07-2017

HGNC name	secreted protein, acidic, cysteine-rich (osteonectin)
HGNC id	11219

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Sparc-null mice exhibit significantly more fat accumulation than wild-type mice
	Sparc-null mice develop progressive osteoporosis, due to a defect in bone formation
	Sparc-null mice have lower intraocular pressure (IOP)
	Sparc-null mice had increased synaptic connections in the superior colliculus