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FLASH GENE

Symbol

IL4

contributors: mct/pgu - updated : 09-03-2017

HGNC name	interleukin 4
HGNC id	6014

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

APY10

Susceptibility

to thromboembolic strocke to diabetic peripheral neuropathy (DPN)

Variant & Polymorphism repeat , other	C582T is a predictor of thromboembolic strocke
	intron 3 VNTR polymorphism of the IL4 gene plays an important role in the occurrence of DPN

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

transgenic mice that inappropriatly expressed IL4 under the direction of the proximal promoter for the lymphocyte-specific protein tyrosine kinase gene (lck/IL4) developed severe osteoporosis