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FLASH GENE

Symbol

MCM3

contributors: mct/npt/shn - updated : 11-11-2012

HGNC name	minichromosome maintenance complex component 3
HGNC id	6945

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in astrocytic tumors tumoral     --other   deregulation might be involved in medulloblastoma tumorigenesis (Lau 2010)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

excess accumulation of MCM3 protein onto chromatin may inhibit DNA replication