Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ALDH7A1 | contributors: mct/npt - updated : 09-04-2008 |
HGNC name | aldehyde dehydrogenase 7 family, member A1 |
HGNC id | 877 |
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Corresponding disease |
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Location | 5q23.2 Physical location : 125.878.917 - 125.931.082 | ||
Synonym name | |||
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Synonym symbol(s) | ATQ1, PDE, FLJ11738, FLJ92814 | ||
EC.number | 1.2.1.3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 52.16 kb 18 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | homolog to green pea |
Homologene |
FAMILY |
CATEGORY | enzyme , regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | sensory transduction/hearing |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | EPD |
Susceptibility | to low-trauma osteoporotic fractures (OF) |
Variant & Polymorphism SNP | SNP, rs13182402 within the ALDH7A1 gene on chromosome 5q31, was strongly associated with OF (Guo 2010) |
Candidate gene | potential candidate gene contributing to the risk of osteoporosis (Guo 2010) | |
Marker
Therapy target
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ANIMAL & CELL MODELS |