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FLASH GENE

Symbol

PPARD

contributors: mct/npt/pgu - updated : 08-06-2016

HGNC name	peroxisome proliferator-activated receptor delta
HGNC id	9235

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	targeted disruption of the mouse peroxisome proliferator-activated receptor beta results in growth, adipose, brain and skin alterations
	endothelial-protective effect of Ppard agonists in diabetic mice through PI3K/Akt/eNOS signaling, suggesting the therapeutic potential of PPARD agonists for diabetic vasculopathy
	long-term cardiomyocyte-restricted PPARdelta deficiency in mice leads to depressed myocardial fatty acid oxidation, bioenergetics, and premature death with lipotoxic cardiomyopathy