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FLASH GENE
Symbol T contributors: mct - updated : 29-12-2016
HGNC name T, brachyury homolog (mouse)
HGNC id 11515
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
low expressed in lung tumors
Susceptibility
  • to spina-bifida (OMIM 182940)
  • to familial chordoma
  • Variant & Polymorphism SNP , other
  • TIVS7 T/C associated with the risk of spina-bifida
  • duplication in familial chordoma (Yang 2009)
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • transgenic null allele mice (Abe, 2000)