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FLASH GENE

Symbol

TRDN

contributors: mct/npt - updated : 09-05-2017

HGNC name	triadin
HGNC id	12261

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CPVT5

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional         displayed extensive T-wave inversions in precordial leads V1 through V4, with either persistent or transient QT prolongation and severe disease expression of exercise-induced cardiac arrest in early childhood

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

triadin KO mouse presents objective muscle dysfunctions and is, therefore, undoubtedly suffering from myopathy as identical energy consumption produced a reduced strength (Oddoux 2009)