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FLASH GENE
Symbol LST1 contributors: - updated : 18-05-2004
HGNC name leukocyte specific transcript 1
HGNC id 14189
RNA
TRANSCRIPTS type messenger
text several alternatively spliced isoforms (I,S) (de Baey,Rollinger-Holzinjer)
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1000 30 190 - -
14
- - - 640 - 97 - de Baey
- - - 630 - 91 - de Baey
- - 500 - 53 - de Baey
- - 310 - 43 - Rollinger-Holzinjer
- - 360 - 59 - Rollinger-Holzinjer
- - 240 - 47 - Rollinger-Holzinjer
- - 290 - 35 - Rollinger-Holzinjer
- - 220 - 13 - Rollinger-Holzinjer
- - 800 - - - Abraham
- - 1200 - 117 - Nalabolu
- splicing 500 - 53 - de Baey
- splicing 640 - 97 - de Baey
- splicing 630 - 91 - de Baey
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • a 120AA extracellular region forming a V-type Ig-like domain with two potential N glycosylation sites
  • a 33aa cytoplasmic tail lacking an immunoreceptor tyrosine-based active motif (ITAM)
    • HOMOLOGY
    interspecies homolog to murine B144 transcript
    homolog to murine B144
    Homologene
    FAMILY
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION interferon gamma inducible protein
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS