Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

MAPK14

contributors: mct/npt/pgu - updated : 19-03-2018

HGNC name	mitogen-activated protein kinase 14
HGNC id	6876

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in myoblasts that are unable to differentiate and form multinucleated myotubes

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular atheroma cardiac FGF1/MAPK14 inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction cancer reproductive ovary pharmacological modulation of genes involved in cancer-specific homeostasis, such as MAPK14, might be exploited to design new therapeutic approaches to cancer treatment

ANIMAL & CELL MODELS

Mapk14 activity is markedly reduced in the livers of obese mice compared with lean mice