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FLASH GENE

Symbol

HTR1B

contributors: mct - updated : 16-01-2006

HGNC name	5-hydroxytryptamine (serotonin) receptor 1B
HGNC id	5287

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in depression-like states

Susceptibility

to attention-deficit/hyperactivity disorder with preferential transmission of paternal alleles to suicide

Variant & Polymorphism other	A-161T locus, which seems to impact HTR1B transcription, could play a role in suicide predisposition by means of mediating impulsive-aggressive behaviors

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS