Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

PBX2

contributors: mct/npt - updated : 07-03-2017

HGNC name	pre-B-cell leukemia homeobox 2
HGNC id	8633

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   leads to PBX1 haploinsufficiency and specific malformations that resemble tetralogy of Fallot, overriding aorta with ventricular septal defect, and bicuspid aortic valves (Stankunas 2008) tumoral     --over   correlated with prognosis of non-small cell lung carcinoma (Qiu 2009)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target	target molecule for treatment of non-small cell lung carcinoma (Qiu 2009)

ANIMAL & CELL MODELS