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FLASH GENE
Symbol GRIK2 contributors: mlm/pgu - updated : 11-04-2019
HGNC name glutamate receptor, ionotropic, kainate 2
HGNC id 4580
ASSOCIATED DISORDERS
corresponding disease(s) MRT6
Susceptibility
  • may be associated with susceptibility for obsessive-compulsive disorder
  • to chronic fatigue syndrome (CFS)
  • Variant & Polymorphism SNP
  • G allele of rs2247215 (GRIK2) were more likely to have CFS and CFS subjects showed decreased GRIK2 expression
  • Candidate gene
  • for AUTS18
  • may be involved in the excitotoxicity in the pathogenesis of Huntington disease
  • Marker
    Therapy target
    ANIMAL & CELL MODELS