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FLASH GENE
Symbol STK19 contributors: npt/ - updated : 02-10-2007
HGNC name serine/threonine kinase 19
HGNC id 11398
DNA
TYPE functioning gene
SPECIAL FEATURE head to head, opposite orientation
text head to head with DOM3Z
STRUCTURE 9.58 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
cytosine-phosphate-guanine/HTF
motif repetitive sequence   ALU   other
text structure
  • a SVA element (SINE/VNTR/Alu) in intron 4
  • 8 alu elements in intron 4
  • common 5' regulatory region of each gene with unmethylated CpG sequence
    • MAPPING cloned Y linked   status confirmed
    Map see HTFAG@ ,TNXB
    RNA
    TRANSCRIPTS type messenger
    text four isoforms by alternative splicing
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 1620 40.5 364 - Shen, 94
    - splicing 1632 40.9 368 - Shen
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelial    
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticmonocyte
    Digestivehepatocyte
    Lymphoid/Immunelymphocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		putative nuclear localization motif,multiple potential phosphorylation,two amidation and nine potential N-myristoylation sites
    HOMOLOGY
    interspecies homolog to murine Stk19
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION serine/threonine kinase
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    manganese Mn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS