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FLASH GENE

Symbol

MSX2

contributors: mct/npt/pgu - updated : 18-09-2015

HGNC name	msh homeobox 2
HGNC id	7392

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	defects in bone growth and ectodermal organ formation in Msx2 deficient mice, premature cranial suture closure
	expression of the Msx2 homeobox gene, an essential regulator of calvarial bone development is absent in the skull mesenchymal progenitors of Foxc1 mutant mice
	Msx1;Msx2 double mutants are characterized by the loss of derivatives of the anterior limb mesoderm which is not observed in either of the simple mutants