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FLASH GENE

Symbol

ADCY2

contributors: mct/npt - updated : 24-04-2009

HGNC name	adenylate cyclase 2 (brain)
HGNC id	233

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	434.00 kb     25 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

Map	pter - D5S1421 - D5S2441 - [D5S1736 - D5S1868 - D5S574 - D5S518 - D5S1957 - D5S208 ] - D5S2088 - D5S1880 - D5S657 - D5S1842 - D5S405 - D5S721 - D5S791 - D5S630 - D5S2046 - D5S23 - D5S1486 - D5S1976 - D5S2095 - D5S759 - D5S1521 - D5S2004 - D5S475 - D5S438E - D5S2480 - D5S2571 - D5S432 - D5S478 - D5S2317 - D5S667 - cen
Authors	Peterson (99)
Text	[ADCY2 ]

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 25 - 6553 - 1091 - Ludwig (2002)

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous nerve       highly Reproductive female system breast mammary gland     Respiratory respiratory tract trachea     highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

two homologous domain

conjugated

GlycoP

HOMOLOGY

Homologene

FAMILY

adenyl cyclase class 4/guanylyl cyclase family

CATEGORY

enzyme , signaling

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

adenylyl cyclase, type II, calmodulin insensitive, may be involved in cAMP biosynthesis, intracellular signaling cascade

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

purine/pyrimidine

signaling

signal transduction

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS