Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

HMGCR

contributors: mct/ - updated : 28-01-2020

HGNC name	3-hydroxy-3-methylglutaryl-Coenzyme A reductase
HGNC id	5006

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LGMDR28

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in gastric cancer and promotes the growth and migration of the cancer cells

Susceptibility

to Alzheimer disease (AD)

Variant & Polymorphism SNP	HMGCR (rs3846662) plays a vital role in AD pathology mainly by influencing brain structure and glucose metabolism during AD progression

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive stomach is a promising therapeutic targetin gastric cancer

ANIMAL & CELL MODELS