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FLASH GENE
Symbol HLA-DRA contributors: mct - updated : 21-04-2008
HGNC name major histocompatibility complex, class II, DR alpha
HGNC id 4947
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a leader peptide,
  • two extracellular domains,
  • a transmembrane domain and a cytoplasmic tail
    • mono polymer heteromer , dimer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,lysosome
    basic FUNCTION plays a central role in the immune system by presenting peptides derived from extracellular proteins
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component heterodimer consisting of an alpha and a beta chain
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS