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FLASH GENE

Symbol

HLA-C

contributors: npt/ - updated : 26-09-2007

HGNC name	major histocompatibility complex, class I, C
HGNC id	4933

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to psoriasis (PSORS1) multinodular goiter to metastatic progression of melanoma to Graves disease

Variant & Polymorphism other	HLA-Cw4 allele can act as a protector against the development of multinodular goiter
	alleles (HLA-C(Lys80)) seem to be associated with metastatic progression of melanoma

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS