Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GABRA1 | contributors: mct - updated : 28-01-2012 |
HGNC name | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
HGNC id | 4075 |
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Corresponding disease |
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Location | 5q33.2 Physical location : 161.274.196 - 161.326.963 | ||||
Synonym symbol(s) | GAA1, GABAAR-alpha1 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
STRUCTURE | 52.77 kb 11 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | Y | status | confirmed |
Map | cen - D5S2916 - D5S380 - D5S2917 - ADRA1B - D5S403 - D5S429 - GABRB2 - GABRA6 - GABRA1 - GABRG2 - D5S422 - HMMR - qter |
Authors | Westbrook (92), Kostrzewa (98) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to murine Gabra1 |
Homologene |
FAMILY | ligand-gated ionic channel family |
CATEGORY | receptor membrane , transport channel |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | |
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basic FUNCTION | |
the GABA/benzodiazepine receptor and opening an integral chloride channel |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | EJM5 , EIEE19 |
Other morbid association(s) |
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Susceptibility |
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Variant & Polymorphism SNP | increasing the risk of schizophrenia |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |