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FLASH GENE

Symbol

CPS1

contributors: mct - updated : 20-01-2016

HGNC name	carbamoyl-phosphate synthetase 1, mitochondrial
HGNC id	2323

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CPS1D

related resource

MITOP database

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   silenced or down-regulated in liver tumor tissues compared with the matched noncancerous tissues tumoral     --low   complete loss in the invasive small-intestinal adenocarcinoma

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	CPS1 gene hypermethylation of the two CpG dinucleotides is a potential biomarker for hepatocellular carcinoma (
	may be a useful prognostic biomarker in human and mouse liver injury
Therapy target

ANIMAL & CELL MODELS