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FLASH GENE

Symbol

AVP

contributors: mct - updated : 02-04-2016

HGNC name	arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal)
HGNC id	894

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DIR3

related resource

Neprhogenic diabetes Insipidus

Susceptibility

to diabetes mellitus

Variant & Polymorphism other	elevated copeptin predicts increased risk for diabetes mellitus independently of established clinical risk factors, including fasting glucose and insulin

Candidate gene
Marker	copeptin is a new promising prognostic marker for short-term mortality independently and additive to natriuretic peptide levels in patients with acute dyspnea
	ischemia-modified albumin (IMA) and AVP detection is clinically useful in the early diagnosis and prognosis of acute carbon monoxide poisoning (ACOP)-related myocardial injury and in guiding early clinical drug application
	AVP and ENO2 measured in the early postnatal period are potential prognostic biomarkers of long-term neurodevelopmental outcome in term neonates diagnosed with hypoxic-ischemic encephalopathy (HIE) and treated with therapeutic hypothermia
Therapy target
	System Type Disorder Pubmed cardiovascular atheroma   AVP system may be a therapeutic target in post-myocardial infarction left ventricular dysfunction

ANIMAL & CELL MODELS