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FLASH GENE
Symbol ALPP contributors: npt/mct - updated : 28-01-2015
HGNC name alkaline phosphatase, placental (Regan isozyme)
HGNC id 439
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --other  
ectopically expressed by cancer cells, in seminoma
Susceptibility
  • to abortion
  • to deleterious action of maternal smoke on intrauterine survival and birthweight
  • Variant & Polymorphism other
  • isoform PLAPD increased in spontaneous abortion
  • polymorphisms increasing deleterious action of maternal smoke on intrauterine survival and birthweight in women older than 28 years
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS