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FLASH GENE
Symbol ALPI contributors: np/ - updated : 02-02-2004
HGNC name alkaline phosphatase, intestinal
HGNC id 437
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • zinc-metalloprotein, made of a complex of identical subunits, each subunit containing one active site
  • two zinc Zn2+ molecules, and magnesium Mg2+as a cofactor
    • conjugated MetalloP
    mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • alkaline phosphatase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text Attached to the membrane by a GPI-anchor
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Zn2+
  • Mg2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS