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FLASH GENE

Symbol

ALPI

contributors: np/ - updated : 02-02-2004

HGNC name	alkaline phosphatase, intestinal
HGNC id	437

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	untranslated

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001631 11 - 2559 NP_001622 54.7 528 - -

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	zinc-metalloprotein, made of a complex of identical subunits, each subunit containing one active site
	two zinc Zn2+ molecules, and magnesium Mg2+as a cofactor

conjugated

MetalloP

mono polymer

homomer , dimer

HOMOLOGY

Homologene

FAMILY

alkaline phosphatase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	plasma membrane
text	Attached to the membrane by a GPI-anchor

basic FUNCTION

unknown

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding, cofactor,
	Zn2+
	Mg2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS