Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | AHCY | contributors: mct - updated : 13-04-2004 |
HGNC name | S-adenosylhomocysteine hydrolase |
HGNC id | 343 |
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Corresponding disease |
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Location | 20q11.22 Physical location : 32.868.072 - 32.899.608 | ||
Synonym name | adenosylhomocysteinase | ||
Synonym symbol(s) | SAHH | ||
EC.number | 3.3.1.1 |
DNA |
TYPE | functioning gene |
STRUCTURE | 23.00 kb 10 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | fetal |
Text | pancreas |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
mono polymer | homomer , tetramer |
HOMOLOGY |
interspecies | ortholog to murine Ahcy |
Homologene |
FAMILY | S-adenosyl-homocysteine hydrolase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm |
basic FUNCTION | |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | aminoacid |
signaling |
sulfur aminoacid |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
NAD |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | AHCYD |
Susceptibility | to abdominal aortic aneurysm (Giusti 2008) |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |