basic FUNCTION
| twelfth step of the de novo purine (adenylate) biosynthesis, component of a bifunctional enzyme also catalyzing the eight step of the de novo purine biosynthesis, i.e, the conversion of SAICAR to AICAR (aminoimidazole carboxamide ribonucleotide) |
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involved in the purine nucleotide cycle |
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role of ADSL-mediated de novo purine synthesis in fueling mitochondrial ATP production to promote liver cancer cell growth |
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ADSL is an oncogene of Prostate carcinoma through regulating the cell cycle pathway firstly, with explicit cell and clinical phenotypes |
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ADSL functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle |