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FLASH GENE
Symbol CHRNA4 contributors: mct - updated : 18-09-2012
HGNC name cholinergic receptor, nicotinic, alpha polypeptide 4
HGNC id 1958
ASSOCIATED DISORDERS
corresponding disease(s) ENFL1
Susceptibility
  • to nicotine addiction
  • to attentional network deficits
  • to sporadic amyotrophic lateral sclerosis
  • Variant & Polymorphism SNP , other
  • variations in CHRNA4 exon 5 associated with attentional network deficits
  • missense variants are associated with sporadic amyotrophic lateral sclerosis
  • rs1044396 affects attention and negative emotionality in normal adults
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS