Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CHRNA4 | contributors: mct - updated : 18-09-2012 |
HGNC name | cholinergic receptor, nicotinic, alpha polypeptide 4 |
HGNC id | 1958 |
|
Corresponding disease |
| ||
Location | 20q13.33 Physical location : 61.974.664 - 61.992.695 | ||
Synonym name | |||
Synonym symbol(s) | BFNC, EBN, EBN1, NACRA4, NACHR, NACHRA4 |
DNA |
TYPE | functioning gene |
STRUCTURE | 18.09 kb 6 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D20S24 - CHRNA4 - D20S20 - qter |
Authors | Steinlein (94) |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | embryo |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
| |
|
conjugated | GlycoP |
mono polymer | heteromer , pentamer |
HOMOLOGY |
Homologene |
FAMILY | cholinergic receptor family |
CATEGORY | receptor membrane ligand ion channel |
SUBCELLULAR LOCALIZATION | plasma membrane |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
a component | heteropentamer alpha 4(2), beta 2 (3subunits) |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | ENFL1 |
Susceptibility |
|
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |