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FLASH GENE
Symbol IL12A contributors: mct - updated : 14-04-2017
HGNC name interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
HGNC id 5969
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in gastric carcinoma with poor prognosis
Susceptibility
  • to systemic lupus erythematosus patients (SLE)
  • to primary biliary cirrhosis (PBC)
  • Variant & Polymorphism SNP SNPs within SCHIP1 (located ~100 kb proximal to IL12A) showed suggestive association with PBC
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    immunologyautoimmuneLupus
    may be therapeutic targets in SLE
    ANIMAL & CELL MODELS